I'm not one to use literature as a base of canon - but I find it particularly interesting that in "War of the Spider Queen" drow were chomping at the bit to kill Lloth.
Drow don't serve Lloth because they love her. They serve Lloth because it's a means of obtaining power. If the matron mothers (or other priestesses) aren't around in game, then the reality in game is that Lloth isn't a great means of obtaining power anymore...which significantly lowers her value to the ambitious drow.
Keep in mind there are one or two other gods ambitious male drows are encouraged to follow. So Eilistraee, Vhaeraun, Selvetarm, and Kiaransalee are all dead or gone - you still have Ghaunadaur.
And one out of five major drow deities ain't bad
War of the Spider Queen not only showed how ungrateful drow are to their gods, but how incredibly vulnerable the gods are when the drow decide it's time to make a move. Very neat idea, that I think would be cool to push down there.
Listen up! People pay good money to see this movie! When they go out to a theater they want cold sodas, hot popcorn, and no monsters in the projection booth! Do I have to come up there myself? Do you think the Gremsters can stand up to the Hulkster?